Frontiers in Molecular Genetics and Genomics (Volume -2)
Keywords:
Molecular Genetics, Genomics, Genome Editing, Functional Genomics, BioinformaticsSynopsis
Frontiers in Molecular Genetics and Genomics (Volume–2) presents a collection of scholarly contributions that explore the latest developments in molecular genetics and genomics and their growing impact on biological research, medicine, agriculture, and biotechnology. The volume provides a broad understanding of how advances in genomic technologies are helping scientists unravel the complexity of genes, genomes, and their functions in living organisms. The chapters discuss important topics such as genome sequencing, gene expression, epigenetics, transcriptomics, proteogenomics, molecular markers, and genome editing technologies, offering both fundamental knowledge and practical applications. Particular attention is given to modern tools including next-generation sequencing, CRISPR-based gene editing, bioinformatics platforms, and integrative omics approaches that are revolutionizing scientific discovery. The volume also highlights the role of genomics in improving crop productivity, enhancing disease diagnosis, supporting personalized medicine, conserving biodiversity, and addressing emerging challenges in health and environmental sustainability. Several chapters examine how artificial intelligence, machine learning, and advanced computational methods are being integrated with genomic research to improve data analysis and accelerate innovation. By bringing together diverse perspectives from researchers and experts, this book demonstrates the interdisciplinary nature of modern genetics and the importance of collaborative approaches in advancing scientific knowledge. Designed for students, researchers, academicians, and professionals, the volume serves as a valuable reference that connects foundational concepts with recent breakthroughs and future opportunities. Through its comprehensive coverage and contemporary outlook, Frontiers in Molecular Genetics and Genomics (Volume–2) aims to promote deeper understanding, encourage innovative research, and contribute to the continued progress of genetics and genomics in the twenty-first century.
Chapters
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Structure and Function of Genes and Genomes
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Chromatin Organisation and Epigenetic Regulation
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DNA Replication, Repair and Recombination Mechanisms
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Transcriptional Control and Gene Expression Networks
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Genome Sequencing Technologies and Platforms
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Bioinformatics Tools for Genomic Data Analysis
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Functional Genomics and High-Throughput Screening
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Proteogenomics and Integrative Omics Approaches
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Genome Editing and CRISPR-Cas Systems
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Human Genetic Disorders and Genomic Diagnostics
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Cancer Genomics and Precision Medicine
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Microbial Genomics and Metagenomics
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Plant and Animal Genomics in Agriculture
References
1. Kumar, R., Das, S. P., Choudhury, B. U., Kumar, A., Prakash, N. R., Verma, R., ... & Mishra, V. K. (2024). Advances in genomic tools for plant breeding: harnessing DNA molecular markers, genomic selection, and genome editing. Biological Research, 57(1), 80.
2. Li, H., Yang, Y., Hong, W., Huang, M., Wu, M., & Zhao, X. (2020). Applications of genome editing technology in the targeted therapy of human diseases: mechanisms, advances and prospects. Signal transduction and targeted therapy, 5(1), 1.
3. Nidhi, S., Anand, U., Oleksak, P., Tripathi, P., Lal, J. A., Thomas, G., ... & Tripathi, V. (2021). Novel CRISPR–Cas systems: an updated review of the current achievements, applications, and future research perspectives. International journal of molecular sciences, 22(7), 3327.
4. Uzair, M., Ain, S., Ain, Q., Kumar, B., Kumar, V., & Pandey, S. (2026). CRISPR-Cas Systems in Targeted Drug Delivery and Gene Therapy: An Emerging Approach to Precision Medicine. International Journal of Research in Pharmacy and Allied Science, 5(2), 66-87.
5. Wang, Y., Zafar, N., Ali, Q., Manghwar, H., Wang, G., Yu, L., ... & Jin, S. (2022). CRISPR/Cas genome editing technologies for plant improvement against biotic and abiotic stresses: advances, limitations, and future perspectives. Cells, 11(23), 3928.
6. Yang, Y., Wang, D., Lü, P., Ma, S., & Chen, K. (2023). Research progress on nucleic acid detection and genome editing of CRISPR/Cas12 system. Molecular biology reports, 50(4), 3723-3738.
7. Zhu, H., Li, C., & Gao, C. (2020). Applications of CRISPR–Cas in agriculture and plant biotechnology. Nature Reviews Molecular Cell Biology, 21(11), 661-677.
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